Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19264379 | 0.88 | HRH3 (0.37) | HRH3CHRNA7 | |
| SCHEMBL17284601 | 0.86 | HRH3 (0.33) | HRH3L3MBTL3 | |
| SCHEMBL17284588 | 0.86 | HRH3 (0.33) | HRH3L3MBTL3 | |
| SCHEMBL17284481 | 0.86 | HRH3 (0.33) | HRH3L3MBTL3 | |
| SCHEMBL14971171 | 0.78 | HRH3 (0.36) | HRH3L3MBTL3CHRM2 | |
| SCHEMBL22211389 | 0.78 | HRH3 (0.36) | HRH3L3MBTL3CHRM2 | |
| SCHEMBL22211388 | 0.78 | HRH3 (0.36) | HRH3L3MBTL3CHRM2 | |
| SCHEMBL23690636 | 0.74 | HRH3 (0.34) | HRH3L3MBTL3CHRM2 | |
| SCHEMBL22211364 | 0.74 | HRH3 (0.34) | HRH3L3MBTL3CHRM2 | |
| SCHEMBL22211358 | 0.74 | HRH3 (0.34) | HRH3L3MBTL3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071447-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS | ANDREWS STEVEN W (US) | 2018-04-19 | — | — | WO | disclosed |