Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22211389 | 0.76 | HRH3 (0.36) | HRH3L3MBTL3CHRM2 | |
| SCHEMBL22211388 | 0.76 | HRH3 (0.36) | HRH3L3MBTL3CHRM2 | |
| SCHEMBL14971171 | 0.76 | HRH3 (0.36) | HRH3L3MBTL3CHRM2 | |
| SCHEMBL20070293 | 0.74 | HRH3 (0.35) | HRH3L3MBTL3CHRM2 | |
| SCHEMBL23690636 | 0.73 | HRH3 (0.34) | HRH3L3MBTL3CHRM2 | |
| SCHEMBL21792599 | 0.73 | HRH3 (0.34) | HRH3L3MBTL3CHRM2 | |
| SCHEMBL22211328 | 0.73 | HRH3 (0.34) | HRH3L3MBTL3CHRM2 | |
| SCHEMBL22211364 | 0.73 | HRH3 (0.34) | HRH3L3MBTL3CHRM2 | |
| SCHEMBL12143914 | 0.72 | — | — | |
| SCHEMBL17888356 | 0.71 | HRH3 (0.46) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3331886-B1 | DOPAMINE D3 RECEPTOR ANTAGONISTS HAVING A BICYCLO MOIETY | INDIVIOR UK LTD (GB) | 2020-07-15 | — | — | EP | disclosed |