SCHEMBL2007080

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2007175	0.92	DRD3 (0.50)	LMNACNR1HSD17B10POLBMAPT
	SCHEMBL2007077	0.90	CNR1 (0.54)	LMNACNR1MAPTALDH1A1KDM4E
	SCHEMBL2009579	0.89	CNR1 (0.53)	CNR1KDM4ESMN1; SMN2TACR3KCNH2
	SCHEMBL2007046	0.89	CNR1 (0.53)	CNR1KDM4ESMN1; SMN2TACR3KCNH2
	SCHEMBL2002975	0.89	HSP90AA1 (0.57)	HSD17B10MGLLCDK1IGF1RFGFR1
	SCHEMBL2006512	0.89	CNR1 (0.53)	LMNACNR1MAPTALDH1A1KDM4E
	SCHEMBL2004347	0.89	CNR1 (0.57)	LMNACNR1HSD17B10POLBMAPT
	SCHEMBL2009783	0.88	CNR1 (0.51)	LMNACNR1POLBMAPTALDH1A1
	SCHEMBL12569321	0.88	CNR1 (0.51)	LMNACNR1POLBMAPTCDK1
	SCHEMBL2003773	0.87	CNR1 (0.51)	LMNACNR1HSD17B10MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.