Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10111451 | 0.86 | SMN1; SMN2 (0.37) | SMN1; SMN2 | |
| SCHEMBL10128471 | 0.76 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL22282378 | 0.75 | — | — | |
| SCHEMBL2741650 | 0.70 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL17066253 | 0.70 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL23386075 | 0.70 | — | — | |
| SCHEMBL21339483 | 0.70 | TSHR (0.33) | — | |
| SCHEMBL22317788 | 0.70 | — | — | |
| SCHEMBL22302013 | 0.70 | — | — | |
| SCHEMBL15912391 | 0.70 | CRHBP (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071447-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS | ANDREWS STEVEN W (US) | 2018-04-19 | — | — | WO | disclosed |