SCHEMBL20071464

SCHEMBL20071464

c1ccc(-c2cc(-c3ccccc3)cc(-n3c4ccccc4c4ccc5ccc6c(c7cccc8c9ccccc9n6c87)c5c43)c2)cc1

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ERBB2 P04626 1/20 0.31
CYP1A2 P05177 1/20 0.31
FYN P06241 1/20 0.31
MAOA P21397 1/20 0.31
ACHE P22303 1/20 0.31
AHR P35869 1/20 0.31
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19890658 0.88 KDM4E (0.36) KDM4EATML3MBTL1ERBB2CYP1A2
SCHEMBL17990405 0.85 L3MBTL1 (0.45) KDM4EATML3MBTL1MEN1ALDH1A1
SCHEMBL15073859 0.83 L3MBTL1 (0.47) KDM4EATML3MBTL1ERBB2CYP1A2
SCHEMBL20071454 0.83 KDM4E (0.43) KDM4EATML3MBTL1MEN1ALDH1A1
SCHEMBL17990475 0.83 L3MBTL1 (0.43) KDM4EATML3MBTL1MEN1ALDH1A1
SCHEMBL20071470 0.83 CYP1A2 (0.32) KDM4EATML3MBTL1ERBB2CYP1A2
SCHEMBL20071370 0.82 KMT2A (0.36) KDM4EATML3MBTL1MAOAMEN1
SCHEMBL13086797 0.82 KDM4E (0.39) KDM4EATML3MBTL1ERBB2CYP1A2
SCHEMBL22036717 0.82 KDM4E (0.39) KDM4EATML3MBTL1MEN1ALDH1A1
SCHEMBL23474710 0.81 KDM4E (0.36) KDM4EATML3MBTL1MEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018070836-A1 COMPOUND FOR ORGANIC ELECTRONIC DEVICE, ORGANIC ELECTRONIC DEVICE USING SAME AND ELECTRONIC APPARATUS THEREFOR 덕산네오룩스 주식회사 2018-04-19 WO disclosed