SCHEMBL20071682

SCHEMBL20071682

c1ccc2c(c1)ccc1cc(-n3c4ccccc4c4c5ccc6c(c5ccc43)c3cccc4c5ccccc5n6c43)ccc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.37
ERBB2 P04626 1/20 0.37
FYN P06241 1/20 0.37
MAOA P21397 1/20 0.37
ACHE P22303 1/20 0.37
AHR P35869 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.34
KDM4E B2RXH2 2/20 0.34
ATM Q13315 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
ALDH1A1 P00352 4/20 0.33
HSD17B10 Q99714 3/20 0.33
HIF1A Q16665 2/20 0.33
CYP1B1 Q16678 1/20 0.33
HPGD P15428 3/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
CASP1 P29466 1/20 0.31
HPRT1 P00492 1/20 0.31
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21717395 0.87 KDM4E (0.38) L3MBTL1KDM4EATMTDP1ALDH1A1
SCHEMBL24795031 0.85 KDM4E (0.36) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL20068493 0.84 KDM4E (0.33) L3MBTL1KDM4EATMALDH1A1HPGD
SCHEMBL17033808 0.84 HPRT1 (0.35) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL20070548 0.84 CYP1A2 (0.43) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL17033863 0.84 HPRT1 (0.37) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL22722264 0.82 KDM4E (0.43) L3MBTL1KDM4EATMTDP1ALDH1A1
SCHEMBL20071470 0.81 CYP1A2 (0.32) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL20071693 0.81 KDM4E (0.44) L3MBTL1KDM4EATMALDH1A1HPGD
SCHEMBL26154789 0.81 KDM4E (0.44) CYP1A2ERBB2FYNMAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018070836-A1 COMPOUND FOR ORGANIC ELECTRONIC DEVICE, ORGANIC ELECTRONIC DEVICE USING SAME AND ELECTRONIC APPARATUS THEREFOR 덕산네오룩스 주식회사 2018-04-19 WO disclosed