SCHEMBL22722264

SCHEMBL22722264

c1ccc(-n2c3ccccc3c3ccc(-n4c5ccccc5c5cccc6c7c8ccccc8ccc7n(c7ccccc74)c56)cc32)cc1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.43
ATM Q13315 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
F2 P00734 1/20 0.33
F10 P00742 1/20 0.33
PRSS1 P07477 1/20 0.33
MAT2A P31153 1/20 0.31
IL1R1 P14778 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30
FOLH1 Q04609 1/20 0.30
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22722284 0.94 L3MBTL1 (0.44) KDM4EATML3MBTL1F2F10
SCHEMBL26771700 0.89 KDM4E (0.36) KDM4EATML3MBTL1MAT2A
SCHEMBL21718280 0.88 KDM4E (0.45) KDM4EATML3MBTL1F2F10
SCHEMBL22722328 0.88 L3MBTL1 (0.41) KDM4EATML3MBTL1IL1R1ALDH1A1
SCHEMBL21717395 0.86 KDM4E (0.38) KDM4EATML3MBTL1TDP1ALDH1A1
SCHEMBL22722266 0.86 KDM4E (0.55) KDM4EATML3MBTL1MAT2AIL1R1
SCHEMBL24767126 0.85 KDM4E (0.47) KDM4EATML3MBTL1MAT2AIL1R1
SCHEMBL23309054 0.85 L3MBTL1 (0.47) KDM4EATML3MBTL1F2F10
SCHEMBL25965206 0.84 KDM4E (0.44) KDM4EATML3MBTL1IL1R1ALDH1A1
SCHEMBL22722313 0.84 L3MBTL1 (0.38) KDM4EATML3MBTL1IL1R1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10854824-B2 Organic electroluminescent compound, organic electroluminescent material and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2020-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10854824-B2 Organic electroluminescent compound, organic electroluminescent material and organic electroluminescent device comprising the same OR10J3, EPCAM, L1CAM KDM4E 1014/4885ATM 1450/4885L3MBTL1 812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.