SCHEMBL20071772

SCHEMBL20071772

COc1ccc2cc(N3c4ccccc4N(c4ccc5cc(OC)ccc5c4)C3C3N(c4ccc5cc(OC)ccc5c4)c4ccccc4N3c3ccc4cc(OC)ccc4c3)ccc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.53
CYP2A6 P11509 1/20 0.53
CYP11B1 P15538 2/20 0.45
CYP11B2 P19099 2/20 0.45
HTR1A P08908 1/20 0.44
HTR1D P28221 1/20 0.44
HTR1B P28222 1/20 0.44
RAB9A P51151 3/20 0.40
NPC1 O15118 2/20 0.40
LMNA P02545 2/20 0.40
KDM4E B2RXH2 2/20 0.40
HSD17B1 P14061 1/20 0.40
HSD17B2 P37059 1/20 0.40
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
POLB P06746 1/20 0.40
NQO2 P16083 1/20 0.40
KMT2A Q03164 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
GRIK1 P39086 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17786071 0.82 HSP90AA1 (0.46) CYP1A2CYP2A6CYP11B1CYP11B2RAB9A
SCHEMBL20071959 0.80 HSP90AA1 (0.40) CYP1A2CYP11B1CYP11B2RAB9ANPC1
SCHEMBL20072022 0.79 CYP2A6 (0.50) CYP1A2CYP2A6RAB9ALMNAMEN1
SCHEMBL19343005 0.78 CYP1A2 (0.55) CYP1A2CYP2A6CYP11B1CYP11B2HTR1A
SCHEMBL20072023 0.77 KCNH2 (0.38) RAB9ANPC1MEN1ALDH1A1KMT2A
SCHEMBL6404071 0.76 CYP1A2 (0.62) CYP1A2CYP2A6CYP11B1CYP11B2HTR1A
SCHEMBL20071828 0.76 CYP1A2 (0.50) CYP1A2CYP2A6CYP11B1CYP11B2HTR1A
SCHEMBL20071832 0.75 CYP2A6 (0.48) CYP1A2CYP2A6RAB9ALMNAMEN1
SCHEMBL13623272 0.73 CYP2A6 (0.49) CYP1A2CYP2A6CYP11B1CYP11B2HTR1A
SCHEMBL20071762 0.72 ALDH1A1 (0.47) CYP1A2CYP2A6KDM4EALDH1A1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed