SCHEMBL20072332

SCHEMBL20072332

CC(C1CCCCC1)S(C)(=O)=O

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.39
CA1 P00915 4/20 0.37
CA12 O43570 4/20 0.37
CA7 P43166 2/20 0.37
CA14 Q9ULX7 2/20 0.37
SHBG P04278 1/20 0.37
ADH1B P00325 1/20 0.35
ADH1C P00326 1/20 0.35
ADH1A P07327 1/20 0.35
EPHX2 P34913 2/20 0.35
CA2 P00918 3/20 0.34
CA9 Q16790 3/20 0.34
MMP2 P08253 2/20 0.34
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2492271 0.78 EPHX1 (0.43) EPHX1CA1CA12CA7CA14
SCHEMBL6058667 0.78 EPHX1 (0.43) EPHX1CA1CA12CA7CA14
SCHEMBL15668553 0.78 CA1 (0.43) EPHX1CA1CA12CA7CA14
Fluoride SCHEMBL19584764 0.76 EPHX1 (0.41) EPHX1CA1CA12CA7CA14
SCHEMBL4072059 0.75 EPHX1 (0.39) EPHX1CA1CA12CA7CA14
SCHEMBL23841199 0.75 EPHX1 (0.35) EPHX1CA1CA12CA7CA14
SCHEMBL2589254 0.73 EPHX1 (0.43) EPHX1CA1CA12CA7CA14
SCHEMBL11746830 0.72 CA1 (0.35) EPHX1CA1CA12CA7CA14
SCHEMBL1672558 0.71 ALDH1A1 (0.50) EPHX1CA1CA12CA7CA14
SCHEMBL23064382 0.70 CA1 (0.34) EPHX1CA1CA12CA7CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3526239-B1 HIF 1-ALPHA ANTISENSE OLIGONUCLEOTIDES OLIPASS CORP (KR) 2021-11-03 EP disclosed
US-20190345202-A1 ANDROGEN RECEPTOR ANTISENSE OLIGONUCLEOTIDES OLIPASS CORPORATION (KR) 2019-11-14 US disclosed
WO-2018069764-A1 HIF 1-ALPHA ANTISENSE OLIGONUCLEOTIDES OLIPASS CORPORATION (KR) 2018-04-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190345202-A1 ANDROGEN RECEPTOR ANTISENSE OLIGONUCLEOTIDES AR, NR5A1, NR5A2 EPHX1 4786/4885CA1 4802/4885CA12 4259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.