SCHEMBL2007288

SCHEMBL2007288

C=CC(c1ccccc1)c1ccccc1.N=C=O.N=C=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.53
MAPT P10636 5/20 0.53
CYP3A4 P08684 4/20 0.53
ALOX15 P16050 3/20 0.53
HPGD P15428 4/20 0.46
LMNA P02545 4/20 0.46
ALDH1A1 P00352 3/20 0.46
USP2 O75604 2/20 0.46
TP53 P04637 2/20 0.46
HSD17B10 Q99714 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
ALOX12 P18054 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
CYP2C19 P33261 1/20 0.37
PPARG P37231 1/20 0.35
PPARD Q03181 1/20 0.35
PPARA Q07869 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL246438 0.86 KDM4E (0.53) KDM4EMAPTCYP3A4ALOX15HPGD
Ammonia Solution, Strong SCHEMBL27626967 0.84 KDM4E (0.52) KDM4EMAPTCYP3A4ALOX15HPGD
SCHEMBL28639731 0.84 KDM4E (0.52) KDM4EMAPTCYP3A4ALOX15HPGD
SCHEMBL11747196 0.76 CYP2C19 (0.37) KDM4EMAPTCYP3A4ALOX15HPGD
Isopropylbenzene SCHEMBL3075578 0.75 TYR (0.38) KDM4EMAPTCYP3A4ALOX15HPGD
SCHEMBL7070422 0.75 CYP2C19 (0.52) KDM4EMAPTCYP3A4ALOX15ALDH1A1
SCHEMBL4561310 0.75 SRC (0.37) KDM4EMAPTCYP3A4ALOX15LMNA
SCHEMBL8694959 0.74 KDM4E (0.44) KDM4EMAPTCYP3A4ALOX15HPGD
SCHEMBL3748518 0.74 KDM4E (0.50) KDM4EMAPTCYP3A4ALOX15HPGD
SCHEMBL28278739 0.74 KDM4E (0.44) KDM4EMAPTCYP3A4ALOX15HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2513238-B1 AQUEOUS COATING COMPOSITION COATINGS FOREIGN IP CO LLC (US) 2014-03-12 EP disclosed
EP-2690143-A1 Powder coating with anodizing effect E.I. DUPONT DE NEMOURS AND COMPANY (US) 2014-01-29 EP disclosed
US-20140024743-A1 Aqueous Coating Composition U S COATINGS IP CO LLC (US) 2014-01-23 US disclosed
EP-2513238-A2 AQUEOUS COATING COMPOSITION E.I. Du Pont De Nemours And Company (US) 2012-10-24 EP disclosed
WO-2011084464-A2 AQUEOUS COATING COMPOSITION E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-07-14 WO disclosed
US-20110151264-A1 AQUEOUS COATING COMPOSITION E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-06-23 US disclosed
EP-2214917-A1 PROCESS OF DECORATION OF POWDER COATED SUBSTRATES E. I. du Pont de Nemours and Company (US) 2010-08-11 EP disclosed
EP-2102264-A1 ANTI-GRAFFITY POWDER COATING COMPOSITION E. I. Du Pont de Nemours and Company (US) 2009-09-23 EP disclosed
WO-2009070527-A1 PROCESS OF DECORATION OF POWDER COATED SUBSTRATES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-06-04 WO disclosed
EP-2065218-A1 Process of decoration of powder coated substrates DuPont Powder Coatings Ibérica, S.L. (ES) 2009-06-03 EP disclosed
US-20090018263-A1 Anti-graffiti powder coating composition AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) 2009-01-15 US disclosed
EP-1942124-A1 Anti-graffity powder coating composition DuPont Powder Coatings Ibérica, S.L. (ES) 2008-07-09 EP disclosed
WO-2008079231-A1 ANTI-GRAFFITY POWDER COATING COMPOSITION E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-07-03 WO disclosed
WO-2008058703-A1 SOLVENT-FREE LAMINATING ADHESIVE BOSTIK S.A. (FR) 2008-05-22 WO disclosed
WO-2007138096-A1 PROCESS OF HIGH SPEED LAMINATING BOSTIK SA (FR) 2007-12-06 WO disclosed