SCHEMBL246438

SCHEMBL246438

C=CC(c1ccccc1)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.53
MAPT P10636 4/20 0.53
CYP3A4 P08684 4/20 0.53
ALOX15 P16050 3/20 0.53
HPGD P15428 3/20 0.46
USP2 O75604 2/20 0.46
TP53 P04637 2/20 0.46
HSD17B10 Q99714 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
ALDH1A1 P00352 2/20 0.46
LMNA P02545 2/20 0.46
ALOX12 P18054 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
TSHR P16473 2/20 0.41
DPP4 P27487 2/20 0.41
F2 P00734 1/20 0.41
CYP2C19 P33261 1/20 0.40
HTR2A P28223 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL27626967 0.97 KDM4E (0.52) KDM4EMAPTCYP3A4ALOX15HPGD
SCHEMBL28639731 0.97 KDM4E (0.52) KDM4EMAPTCYP3A4ALOX15HPGD
SCHEMBL8694959 0.86 KDM4E (0.44) KDM4EMAPTCYP3A4ALOX15HPGD
SCHEMBL28278739 0.86 KDM4E (0.44) KDM4EMAPTCYP3A4ALOX15HPGD
SCHEMBL2007288 0.86 KDM4E (0.53) KDM4EMAPTCYP3A4ALOX15HPGD
SCHEMBL3748518 0.86 KDM4E (0.50) KDM4EMAPTCYP3A4ALOX15HPGD
SCHEMBL25948224 0.86 KDM4E (0.44) KDM4EMAPTCYP3A4ALOX15HPGD
SCHEMBL24065953 0.81 MAPT (0.53) KDM4EMAPTCYP3A4ALOX15HPGD
SCHEMBL27820984 0.81 KDM4E (0.41) KDM4EMAPTCYP3A4ALOX15HPGD
SCHEMBL28307922 0.81 CFTR (0.57) KDM4EMAPTCYP3A4ALOX15ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115279874-B Grease composition 出光兴产株式会社 2024-02-13 CN claimed
CN-115279875-B Grease composition 出光兴产株式会社 2024-01-12 CN claimed
CN-113490734-B Grease composition 出光兴产株式会社 2023-08-01 CN claimed
CN-113490733-B Grease composition, and method and device for lubricating sliding mechanism using same 出光兴产株式会社 2023-07-28 CN claimed
CN-113508171-B Grease composition 出光兴产株式会社 2023-06-06 CN claimed
CN-113348234-B Grease composition 出光兴产株式会社 2023-03-21 CN claimed
CN-110546245-B Grease composition 出光兴产株式会社 2023-01-31 CN claimed
CN-112639060-B Grease composition for constant velocity joints 出光兴产株式会社 2022-12-09 CN claimed
CN-113480566-A Organic silicon monomer containing diphenylmethane and ultrahigh-refractive-index semiconductor LED packaging material prepared from organic silicon monomer 广州星光有机硅科技有限公司 2021-10-08 CN claimed
CN-104505145-B A kind of conductive silver paste of nickeliferous micropowder 安徽凤阳德诚科技有限公司 2016-09-14 CN claimed
CN-102522140-A Aluminum paste for silicon-based solar cell and preparation method for aluminum paste IRICO GROUP CORP 2012-06-27 CN claimed
CN-101950597-B Silver-aluminum paste for electromagnetic shielding and preparation method thereof IRICO GROUP CORP 2012-05-23 CN claimed
CN-101950597-A Silver aluminum slurry for electromagnetic shielding and preparation method thereof IRICO GROUP CORP 2011-01-19 CN claimed
US-7868118-B2 High refractive index flexible silicone OPHTEC B.V. (NL) 2011-01-11 US claimed
US-20070203317-A1 HIGH REFRACTIVE INDEX FLEXIBLE SILICONE OPHTEC B.V. (NL) 2007-08-30 US claimed
EP-1472305-A1 HIGH REFRACTIVE INDEX FLEXIBLE SILICONE Ophtec B.V. (NL) 2004-11-03 EP claimed
US-20030162929-A1 High refractive index flexible silicone OPHTEC B.V. (NL) 2003-08-28 US claimed
WO-2003066707-A1 HIGH REFRACTIVE INDEX FLEXIBLE SILICONE OPHTEC B.V. (NL) 2003-08-14 WO claimed
EP-1334991-A1 High refractive index flexible silicone Ophtec B.V. (NL) 2003-08-13 EP claimed
US-4369298-A Novel cured resin, process for production thereof, and lens composed of said resin from bis(alkyleneoxyphenyl)-diacrylate, bis(alkyleneoxyphenyl)diallyl ether, bis(alkyleneoxyphenyl)diallyl carbonate monomers TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1983-01-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070203317-A1 HIGH REFRACTIVE INDEX FLEXIBLE SILICONE MACF1, SMCHD1, RPIA KDM4E 1493/4885MAPT 2279/4885CYP3A4 3244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.