Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17664928 | 0.79 | QPCT (0.44) | QPCTHRH4HRH2ALDH1A1CYP1A2 | |
| SCHEMBL19420512 | 0.79 | HRH2 (0.55) | QPCTHRH4HRH2ALDH1A1MEN1 | |
| SCHEMBL10906577 | 0.79 | QPCT (0.44) | QPCTHRH4HRH2ALDH1A1CYP1A2 | |
| SCHEMBL22364147 | 0.79 | QPCT (0.37) | QPCTHRH4HRH2ALDH1A1CYP3A4 | |
| SCHEMBL28998258 | 0.77 | QPCT (0.42) | QPCTHRH4HRH2ALDH1A1CYP1A2 | |
| SCHEMBL12787075 | 0.77 | ALDH1A1 (0.56) | QPCTHRH4HRH2ALDH1A1CYP1A2 | |
| SCHEMBL11504380 | 0.76 | MEN1 (0.52) | QPCTHRH4HRH2ALDH1A1LMNA | |
| SCHEMBL7726899 | 0.73 | — | — | |
| SCHEMBL16000786 | 0.73 | EPHX1 (0.57) | ALDH1A1LMNAMEN1KMT2AEPHX1 | |
| SCHEMBL17670557 | 0.72 | EPHX1 (0.61) | QPCTHRH4HRH2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180104354-A1 | CHIMERIC ANTIGEN RECEPTOR T CELL SWITCHES AND USES THEREOF | THE SCRIPPS RESEARCH INSTITUTE | 2018-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180104354-A1 | CHIMERIC ANTIGEN RECEPTOR T CELL SWITCHES AND USES THEREOF | ICOS, HAVCR2, CD2 | QPCT 2869/4885HRH4 3917/4885HRH2 4127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.