Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GLP1R | P43220 | 8/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25836510 | 0.85 | KMT2A (0.49) | MEN1KMT2AGLP1RTSHRADRB2 | |
| SCHEMBL21106234 | 0.83 | KMT2A (0.61) | MEN1KMT2ATSHRADRB2HTT | |
| SCHEMBL21106165 | 0.83 | KMT2A (0.61) | MEN1KMT2ATSHRADRB2HTT | |
| SCHEMBL18908759 | 0.83 | KMT2A (0.61) | MEN1KMT2ATSHRADRB2HTT | |
| SCHEMBL18908752 | 0.83 | KMT2A (0.61) | MEN1KMT2ATSHRADRB2HTT | |
| SCHEMBL25834730 | 0.83 | KMT2A (0.61) | MEN1KMT2ATSHRADRB2HTT | |
| SCHEMBL23807051 | 0.82 | KMT2A (0.49) | MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL22837695 | 0.82 | KMT2A (0.58) | MEN1KMT2ATSHRHTTSMN1; SMN2 | |
| SCHEMBL22794306 | 0.82 | TSHR (0.53) | MEN1KMT2AGLP1RTSHRHPGD | |
| SCHEMBL26866002 | 0.82 | MEN1 (0.41) | MEN1KMT2AGLP1RTSHRADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180104354-A1 | CHIMERIC ANTIGEN RECEPTOR T CELL SWITCHES AND USES THEREOF | THE SCRIPPS RESEARCH INSTITUTE | 2018-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180104354-A1 | CHIMERIC ANTIGEN RECEPTOR T CELL SWITCHES AND USES THEREOF | ICOS, HAVCR2, CD2 | MEN1 4384/4885KMT2A 1833/4885GLP1R 2991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.