Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.34 |
| ▸ | GLP1R | P43220 | 5/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22837695 | 0.90 | KMT2A (0.58) | KMT2AMEN1KDM4ECYP2D6CYP2C19 | |
| SCHEMBL21106234 | 0.89 | KMT2A (0.61) | KMT2AMEN1KDM4ECYP2D6CYP2C19 | |
| SCHEMBL18908752 | 0.89 | KMT2A (0.61) | KMT2AMEN1KDM4ECYP2D6CYP2C19 | |
| SCHEMBL21106165 | 0.89 | KMT2A (0.61) | KMT2AMEN1KDM4ECYP2D6CYP2C19 | |
| SCHEMBL18908759 | 0.89 | KMT2A (0.61) | KMT2AMEN1KDM4ECYP2D6CYP2C19 | |
| SCHEMBL25834730 | 0.89 | KMT2A (0.61) | KMT2AMEN1KDM4ECYP2D6CYP2C19 | |
| SCHEMBL26034118 | 0.88 | MEN1 (0.41) | KMT2AMEN1KDM4ECYP2D6CYP2C19 | |
| SCHEMBL25836541 | 0.86 | MEN1 (0.42) | KMT2AMEN1KDM4ECYP2D6CYP2C19 | |
| SCHEMBL20073434 | 0.85 | MEN1 (0.47) | KMT2AMEN1ALDH1A1TSHRADRB2 | |
| SCHEMBL24297138 | 0.84 | MEN1 (0.53) | KMT2AMEN1ALDH1A1TSHRGLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230226193-A1 | LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS | Arrowhead Pharmaceuticals, Inc. | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230226193-A1 | LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS | CPT1B, MUSK, MYLK2 | KMT2A 1603/4885MEN1 4753/4885KDM4E 1852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.