Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 12/20 | 0.70 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.70 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.70 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.62 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29330184 | 1.00 | FOLH1 (0.70) | FOLH1NAALAD2RIMKLANOD1SLC6A5 | |
| SCHEMBL11977634 | 0.98 | FOLH1 (0.72) | FOLH1NAALAD2RIMKLANOD1 | |
| SCHEMBL11977636 | 0.98 | FOLH1 (0.72) | FOLH1NAALAD2RIMKLANOD1 | |
| SCHEMBL23221739 | 0.93 | FOLH1 (0.75) | FOLH1NAALAD2RIMKLANOD1 | |
| SCHEMBL20694459 | 0.93 | FOLH1 (0.75) | FOLH1NAALAD2RIMKLANOD1 | |
| SCHEMBL21417883 | 0.88 | FOLH1 (0.67) | FOLH1NAALAD2RIMKLANOD1 | |
| SCHEMBL22237179 | 0.88 | FOLH1 (0.67) | FOLH1NAALAD2RIMKLANOD1 | |
| SCHEMBL15003787 | 0.88 | FOLH1 (0.67) | FOLH1NAALAD2RIMKLANOD1 | |
| SCHEMBL12836737 | 0.88 | FOLH1 (0.67) | FOLH1NAALAD2RIMKLANOD1 | |
| SCHEMBL18030076 | 0.88 | FOLH1 (0.67) | FOLH1NAALAD2RIMKLANOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180104354-A1 | CHIMERIC ANTIGEN RECEPTOR T CELL SWITCHES AND USES THEREOF | THE SCRIPPS RESEARCH INSTITUTE | 2018-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180104354-A1 | CHIMERIC ANTIGEN RECEPTOR T CELL SWITCHES AND USES THEREOF | ICOS, HAVCR2, CD2 | FOLH1 1953/4885NAALAD2 487/4885RIMKLA 3128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.