Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 7/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 12/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL247150 | 0.82 | CRBN (0.50) | CRBNDDB1 | |
| Hydrochloric Acid SCHEMBL30515324 | 0.80 | CRBN (0.49) | CRBN | |
| SCHEMBL1093770 | 0.79 | MAPT (0.53) | IDH1CRBNDDB1 | |
| Maleic Acid SCHEMBL29618262 | 0.75 | CRBN (0.48) | CRBN | |
| SCHEMBL31729609 | 0.74 | GSK3B (0.42) | IDH1CRBNDDB1 | |
| SCHEMBL8621250 | 0.74 | ANPEP (0.42) | IDH1CRBNDDB1 | |
| SCHEMBL22509084 | 0.74 | ANPEP (0.42) | IDH1CRBNDDB1 | |
| SCHEMBL8622452 | 0.74 | GSK3B (0.42) | IDH1CRBNDDB1 | |
| SCHEMBL29415789 | 0.74 | ANPEP (0.42) | IDH1CRBNDDB1 | |
| SCHEMBL2883608 | 0.74 | CRBN (0.42) | IDH1CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018069732-A1 | HETEROCYCLIC COMPOUNDS HAVING ACTIVITY AS MODULATORS OF MUSCARINIC M1 AND/OR M4 RECEPTORS IN THE TREATMENT OF CNS DISEASES AND PAINS. | HEPTARES THERAPEUTICS LIMITED (GB) | 2018-04-19 | — | — | WO | disclosed |