Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 11/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9360186 | 0.98 | SIRT2 (0.40) | SIRT2CYP19A1FAAHMGLL | |
| SCHEMBL9356126 | 0.91 | HSD17B10 (0.36) | SIRT2CYP19A1FAAHMGLLALOX5 | |
| SCHEMBL11846071 | 0.86 | SIRT2 (0.46) | SIRT2GAA | |
| SCHEMBL10188292 | 0.85 | MGLL (0.54) | CYP19A1FAAHMGLL | |
| SCHEMBL19390731 | 0.85 | MGLL (0.54) | CYP19A1FAAHMGLL | |
| SCHEMBL19380742 | 0.85 | MGLL (0.54) | CYP19A1FAAHMGLL | |
| SCHEMBL9356226 | 0.83 | HSD17B10 (0.34) | SIRT2CYP19A1FAAHMGLLGAA | |
| SCHEMBL2223307 | 0.82 | MEN1 (0.32) | CYP19A1 | |
| SCHEMBL16729939 | 0.82 | SIRT2 (0.41) | SIRT2CYP19A1 | |
| SCHEMBL28008290 | 0.79 | TSHR (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018069732-A1 | HETEROCYCLIC COMPOUNDS HAVING ACTIVITY AS MODULATORS OF MUSCARINIC M1 AND/OR M4 RECEPTORS IN THE TREATMENT OF CNS DISEASES AND PAINS. | HEPTARES THERAPEUTICS LIMITED (GB) | 2018-04-19 | — | — | WO | disclosed |