Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15688832 | 1.00 | TSHR (0.49) | TSHRHSD17B10TNNC1MGLLCYP2A6 | |
| SCHEMBL2007392 | 1.00 | TSHR (0.49) | TSHRHSD17B10TNNC1MGLLCYP2A6 | |
| SCHEMBL24352161 | 1.00 | TSHR (0.49) | TSHRHSD17B10TNNC1MGLLCYP2A6 | |
| SCHEMBL15688808 | 1.00 | TSHR (0.49) | TSHRHSD17B10TNNC1MGLLCYP2A6 | |
| SCHEMBL9827727 | 0.98 | TSHR (0.46) | TSHRHSD17B10TNNC1MGLLCYP2A6 | |
| SCHEMBL9827715 | 0.98 | TSHR (0.46) | TSHRHSD17B10TNNC1MGLLCYP2A6 | |
| SCHEMBL9827722 | 0.98 | TSHR (0.46) | TSHRHSD17B10TNNC1MGLLCYP2A6 | |
| SCHEMBL8621675 | 0.94 | TNNC1 (0.43) | TSHRHSD17B10TNNC1MGLLCYP2A6 | |
| SCHEMBL8621670 | 0.94 | TNNC1 (0.43) | TSHRHSD17B10TNNC1MGLLCYP2A6 | |
| SCHEMBL15688739 | 0.93 | TSHR (0.44) | TSHRHSD17B10TNNC1MGLLCYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960571-B2 | Silicon-based cross-coupling reagent and production method of organic compound using the same | KYOTO UNIVERSITY (JP) | 2011-06-14 | — | — | US | disclosed |
| US-20090069577-A1 | Silicon-Based Cross-Coupling Reagent and Production Method of Organic Compound Using the Same | KYOTO UNIVERSITY (JP) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069577-A1 | Silicon-Based Cross-Coupling Reagent and Production Method of Organic Compound Using the Same | DNMT1, TET3, CTCF | TSHR 2074/4885HSD17B10 3287/4885TNNC1 3618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.