Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 5/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20074102 | 0.85 | KDM5B (0.46) | KDM5BKDM5AKDM5CKDM4CBRD4 | |
| SCHEMBL20074099 | 0.83 | KDM5B (0.50) | KDM5BKDM5AKDM5CKDM4CTSHR | |
| SCHEMBL20074093 | 0.81 | KDM5B (0.37) | KDM5BKDM5AKDM5CKDM4CBRD4 | |
| SCHEMBL20074270 | 0.81 | KDM5B (0.51) | KDM5BKDM5AKDM5CKDM4C | |
| SCHEMBL20074321 | 0.75 | KDM5B (0.38) | KDM5BKDM5AKDM5CKDM4CBRD4 | |
| SCHEMBL27328352 | 0.75 | TDP1 (0.41) | TSHR | |
| SCHEMBL20074143 | 0.74 | KDM5B (0.41) | KDM5BKDM5AKDM5CKDM4CTSHR | |
| SCHEMBL21720979 | 0.73 | KDM5B (0.55) | KDM5BKDM5AKDM5CKDM4CTSHR | |
| SCHEMBL20074104 | 0.72 | KDM5B (0.45) | KDM5BKDM5ABRD4TSHR | |
| SCHEMBL20074306 | 0.71 | KDM5B (0.55) | KDM5BKDM5AKDM5CKDM4CTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3525785-B1 | KDM5 INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2025-08-27 | — | — | EP | claimed |
| WO-2018071283-A1 | KDM5 INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2018-04-19 | — | — | WO | disclosed |