Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20074091 | 0.75 | KDM5B (0.39) | TSHR | |
| SCHEMBL20074288 | 0.70 | KDM4E (0.50) | TDP1TP53KDM4EALDH1A1HPGD | |
| SCHEMBL31676989 | 0.68 | KDM5B (0.52) | TDP1TSHR | |
| SCHEMBL21721728 | 0.67 | KDM5B (0.53) | TP53KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20074331 | 0.67 | KDM5B (0.43) | TDP1ALDH1A1TSHRGCGRMAPK14 | |
| SCHEMBL31676967 | 0.66 | KDM5B (0.47) | ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL20074113 | 0.66 | KDM5B (0.44) | TDP1ALDH1A1TSHRADORA2A | |
| SCHEMBL20074103 | 0.66 | KDM5B (0.42) | KDM4EALDH1A1HSD17B10EGLN2LMNA | |
| SCHEMBL21721676 | 0.66 | KDM5B (0.50) | TDP1ALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL31676999 | 0.65 | KDM5B (0.49) | HPGDHSD17B10EGLN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12016863-B2 | Inhibitors of RSV replication and applications thereof | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2024-06-25 | — | — | US | disclosed |
| US-12016863-B2 | Inhibitors of RSV replication and applications thereof | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2024-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12016863-B2 | Inhibitors of RSV replication and applications thereof | SNRPE, PRDX1, PRDX6 | TDP1 2965/4885TP53 4240/4885MDM2 2984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.