Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 20/20 | 0.73 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.73 |
| ▸ | KDR | P35968 | 5/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20074499 | 0.84 | TGFBR1 (1.00) | TGFBR1MAPK14KDR | |
| SCHEMBL20074572 | 0.84 | TGFBR1 (1.00) | TGFBR1MAPK14KDR | |
| SCHEMBL20074407 | 0.84 | TGFBR1 (1.00) | TGFBR1MAPK14KDR | |
| SCHEMBL21712667 | 0.78 | TGFBR1 (0.68) | TGFBR1MAPK14KDR | |
| SCHEMBL20074571 | 0.77 | TGFBR1 (1.00) | TGFBR1MAPK14KDR | |
| SCHEMBL20074402 | 0.75 | TGFBR1 (0.66) | TGFBR1MAPK14KDR | |
| SCHEMBL20074428 | 0.74 | TGFBR1 (0.74) | TGFBR1MAPK14KDR | |
| SCHEMBL21278020 | 0.72 | TGFBR1 (0.63) | TGFBR1MAPK14KDR | |
| SCHEMBL21733992 | 0.72 | TGFBR1 (0.83) | TGFBR1MAPK14KDR | |
| SCHEMBL21277826 | 0.71 | TGFBR1 (1.00) | TGFBR1MAPK14KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018068759-A1 | FIVE-MEMBERED HETEROARYL RING BRIDGED RING DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 江苏恒瑞医药股份有限公司 | 2018-04-19 | — | — | WO | disclosed |