SCHEMBL20075082

SCHEMBL20075082

Cc1cc(C)n(-c2cc(Nc3c(O)c(-c4ccc(C#N)cc4)nn3C)ncn2)n1

nearest known ligand 0.82

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC34A1 Q06495 20/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20074883 0.90 SLC34A1 (1.00) SLC34A1
SCHEMBL20075130 0.89 SLC34A1 (0.84) SLC34A1
SCHEMBL20075069 0.87 SLC34A1 (1.00) SLC34A1
SCHEMBL20075592 0.87 SLC34A1 (1.00) SLC34A1
SCHEMBL20075313 0.84 SLC34A1 (0.82) SLC34A1
SCHEMBL20075018 0.81 SLC34A1 (1.00) SLC34A1
SCHEMBL20075526 0.80 SLC34A1 (1.00) SLC34A1
SCHEMBL20074987 0.79 SLC34A1 (0.87) SLC34A1
SCHEMBL20075394 0.79 SLC34A1 (1.00) SLC34A1
SCHEMBL20075112 0.79 SLC34A1 (1.00) SLC34A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3526212-B1 SUBSTITUTED 6-(1H-PYRAZOL-1-YL)PYRIMIDIN-4-AMINE DERIVATIVES AND USES THEREOF BAYER AG (DE) 2021-12-22 EP disclosed
WO-2018069222-A1 SUBSTITUTED 6-(1H-PYRAZOL-1-YL)PYRIMIDIN-4-AMINE DERIVATIVES AND USES THEREOF BAYER AKTIENGESELLSCHAFT (DE) 2018-04-19 WO disclosed