Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21758267 | 0.86 | L3MBTL1 (0.42) | KDM4EATML3MBTL1PTGS2F2 | |
| SCHEMBL10039116 | 0.78 | KDM4E (0.59) | KDM4EATML3MBTL1PTPN1SLC6A2 | |
| SCHEMBL10100856 | 0.78 | KDM4E (0.59) | KDM4EATML3MBTL1PTPN1SLC6A2 | |
| SCHEMBL13141851 | 0.78 | KDM4E (0.44) | KDM4EATML3MBTL1F2F10 | |
| SCHEMBL13141847 | 0.77 | KDM4E (0.57) | KDM4EATML3MBTL1F2F10 | |
| SCHEMBL19836759 | 0.75 | KDM4E (0.61) | KDM4EATML3MBTL1PTPN1PPARG | |
| SCHEMBL13141865 | 0.75 | L3MBTL1 (0.55) | KDM4EATML3MBTL1PTPN1 | |
| SCHEMBL16482566 | 0.74 | KDM4E (0.53) | KDM4EATML3MBTL1PTPN1PPARG | |
| SCHEMBL24489657 | 0.73 | L3MBTL1 (0.44) | KDM4EATML3MBTL1PTPN1CYP11B1 | |
| SCHEMBL10206300 | 0.73 | KDM4E (0.58) | KDM4EATML3MBTL1PTPN1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018069197-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2018-04-19 | — | — | WO | disclosed |