Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20046423 | 0.87 | SCD (0.46) | GPR119SCDKDM4EPKMALDH1A1 | |
| SCHEMBL23536796 | 0.87 | GPR119 (0.45) | GPR119SCDKDM4EPKMALDH1A1 | |
| SCHEMBL27169461 | 0.87 | SCD (0.45) | GPR119SCDKDM4EPKMALDH1A1 | |
| SCHEMBL30893463 | 0.84 | GPR119 (0.52) | GPR119SCDALDH1A1LMNAMAPT | |
| SCHEMBL23960996 | 0.84 | GPR119 (0.52) | GPR119SCDALDH1A1LMNAMAPT | |
| SCHEMBL25059180 | 0.83 | GPR119 (0.41) | GPR119SCDKDM4EPKMALDH1A1 | |
| SCHEMBL20046676 | 0.83 | HRH3 (0.47) | GPR119SCDALDH1A1 | |
| SCHEMBL20046463 | 0.83 | HRH3 (0.52) | GPR119SCDALDH1A1 | |
| SCHEMBL23572658 | 0.78 | GPR119 (0.45) | GPR119SCDKDM4EPKM | |
| SCHEMBL24379281 | 0.78 | GPR119 (0.45) | GPR119SCDKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071606-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR | Arvinas, Inc. (US) | 2018-04-19 | — | — | WO | disclosed |