⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21449728 | 1.00 | — | — | |
| SCHEMBL10531986 | 1.00 | — | — | |
| SCHEMBL18236002 | 0.79 | — | — | |
| SCHEMBL24610248 | 0.74 | — | — | |
| SCHEMBL16476567 | 0.71 | — | — | |
| SCHEMBL24846590 | 0.69 | — | — | |
| SCHEMBL24658488 | 0.69 | — | — | |
| SCHEMBL13211917 | 0.69 | — | — | |
| SCHEMBL15919042 | 0.67 | — | — | |
| SCHEMBL23229589 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071606-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR | Arvinas, Inc. (US) | 2018-04-19 | — | — | WO | disclosed |