⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24846590 | 0.75 | — | — | |
| SCHEMBL20047061 | 0.74 | — | — | |
| SCHEMBL21449728 | 0.69 | — | — | |
| SCHEMBL20076211 | 0.69 | — | — | |
| SCHEMBL10531986 | 0.69 | — | — | |
| SCHEMBL13271934 | 0.69 | — | — | |
| SCHEMBL24377282 | 0.69 | FURIN (0.39) | — | |
| SCHEMBL13746673 | 0.67 | — | — | |
| SCHEMBL22278215 | 0.67 | — | — | |
| SCHEMBL25541101 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3704112-B1 | ALKENE SPIROCYCLIC COMPOUNDS AS FARNESOID X RECEPTOR MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2023-09-27 | — | — | EP | disclosed |
| WO-2022189856-A9 | COMPOUNDS USEFUL FOR TREATING LIVER DISEASES | ABIONYX PHARMA SA (FR) | 2022-10-13 | — | — | WO | disclosed |