SCHEMBL20076471

SCHEMBL20076471

NC(=O)C1C(c2ccc(Cl)c(Cl)c2)C1(Cl)Cl

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.50
KMT2A Q03164 4/20 0.43
MAPT P10636 2/20 0.43
SLC6A4 P31645 6/20 0.41
SLC6A2 P23975 5/20 0.41
BACE1 P56817 1/20 0.37
SLC9A1 P19634 3/20 0.37
SLC6A3 Q01959 4/20 0.36
TSHR P16473 1/20 0.35
MEN1 O00255 3/20 0.34
KDM4E B2RXH2 1/20 0.34
GAA P10253 1/20 0.34
HTR3E A5X5Y0 1/20 0.33
HTR3B O95264 1/20 0.33
HTR3A P46098 1/20 0.33
HTR3D Q70Z44 1/20 0.33
HTR3C Q8WXA8 1/20 0.33
ALDH1A1 P00352 1/20 0.33
RECQL P46063 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30739935 1.00 NPSR1 (0.50) NPSR1KMT2AMAPTSLC6A4SLC6A2
SCHEMBL30739896 0.86 KMT2A (0.43) NPSR1KMT2AMAPTSLC9A1MEN1
SCHEMBL30739760 0.86 KMT2A (0.43) NPSR1KMT2AMAPTSLC9A1MEN1
SCHEMBL19493390 0.85 NPSR1 (0.44) NPSR1KMT2AMAPTTSHRMEN1
SCHEMBL21022380 0.85 NPSR1 (0.44) NPSR1KMT2AMAPTTSHRMEN1
SCHEMBL18143599 0.85 NPSR1 (0.44) NPSR1KMT2AMAPTTSHRMEN1
SCHEMBL18143601 0.85 NPSR1 (0.44) NPSR1KMT2AMAPTTSHRMEN1
SCHEMBL21019239 0.85 NPSR1 (0.44) NPSR1KMT2AMAPTTSHRMEN1
SCHEMBL21022296 0.85 NPSR1 (0.44) NPSR1KMT2AMAPTSLC6A4SLC6A3
SCHEMBL18143600 0.85 NPSR1 (0.44) NPSR1KMT2AMAPTTSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118044519-A Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-05-17 CN disclosed
CN-110072842-B Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-02-02 CN disclosed
WO-2018071327-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2018-04-19 WO disclosed