SCHEMBL30739896

SCHEMBL30739896

NC(=O)C1C(c2ccc(F)c(Cl)c2)C1(Cl)Cl

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.43
MAPT P10636 1/20 0.43
SLC9A1 P19634 5/20 0.42
MEN1 O00255 1/20 0.39
LMNA P02545 1/20 0.39
IDO1 P14902 4/20 0.38
TDO2 P48775 2/20 0.38
ITGB3 P05106 1/20 0.38
ITGAV P06756 1/20 0.38
NPSR1 Q6W5P4 1/20 0.37
CASP1 P29466 1/20 0.36
SLC2A1 P11166 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30739760 1.00 KMT2A (0.43) KMT2AMAPTSLC9A1MEN1LMNA
SCHEMBL30258023 0.86 MEN1 (0.43) KMT2AMAPTSLC9A1MEN1LMNA
SCHEMBL30739905 0.86 MEN1 (0.40) KMT2ASLC9A1MEN1LMNANPSR1
SCHEMBL18143724 0.86 MEN1 (0.43) KMT2AMAPTSLC9A1MEN1LMNA
SCHEMBL18143726 0.86 MEN1 (0.43) KMT2AMAPTSLC9A1MEN1LMNA
SCHEMBL19442291 0.86 MEN1 (0.43) KMT2AMAPTSLC9A1MEN1LMNA
SCHEMBL18143728 0.86 MEN1 (0.43) KMT2AMAPTSLC9A1MEN1LMNA
SCHEMBL20076620 0.86 SLC9A1 (0.40) KMT2AMAPTSLC9A1MEN1LMNA
SCHEMBL20845981 0.86 MEN1 (0.43) KMT2AMAPTSLC9A1MEN1LMNA
SCHEMBL20076471 0.86 NPSR1 (0.50) KMT2AMAPTSLC9A1MEN1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118044519-A Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-05-17 CN disclosed
CN-110072842-B Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-02-02 CN disclosed