SCHEMBL20076689

SCHEMBL20076689

CCc1ccc(C2C(c3cc(C)cc(C)c3)C2(C)Cl)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.33
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
ATM Q13315 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ABCB1 P08183 1/20 0.31
CYP3A4 P08684 1/20 0.31
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31
KDM4E B2RXH2 2/20 0.30
ALDH1A1 P00352 2/20 0.30
HPGD P15428 2/20 0.30
GAA P10253 1/20 0.30
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
ALOX15 P16050 1/20 0.30
ALOX12 P18054 1/20 0.30
BRCA1 P38398 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21021656 0.92 CNR1 (0.34) NPSR1CNR1CNR2ALDH1A1GAA
SCHEMBL21022090 0.85 CNR2 (0.40) NPSR1TSHRMAPK1ATMTDP1
SCHEMBL20076455 0.82 SLC5A2 (0.34) NPSR1SLC5A1SLC5A2
SCHEMBL21022302 0.80 SLC5A2 (0.32) CNR1CNR2GAAMAPTSLC5A1
SCHEMBL21021542 0.78 SLC9A1 (0.37) ATMSLC5A1SLC5A2
SCHEMBL20076684 0.76 SLC9A1 (0.38) TSHRL3MBTL1KMT2ASLC5A1SLC5A2
SCHEMBL21021657 0.75 KDM1A (0.41) CYP3A4KDM4EALDH1A1MEN1MAPT
SCHEMBL21021762 0.75 SLC9A1 (0.32)
SCHEMBL20076857 0.75 IDH1 (0.33)
SCHEMBL20076432 0.74 MEN1 (0.40) CYP3A4KDM4EALDH1A1HPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018071327-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2018-04-19 WO disclosed