Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND3 | P30281 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27146477 | 0.71 | CSF1R (0.39) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL3583880 | 0.70 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL6420817 | 0.70 | NR1H2 (0.40) | KDM4EHTTSMN1; SMN2TDP1NPSR1 | |
| Hydrochloric Acid SCHEMBL3581051 | 0.69 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL12814344 | 0.69 | MEN1 (0.51) | KDM4EALDH1A1HTTPOLBLMNA | |
| SCHEMBL1031945 | 0.68 | MAPT (0.38) | KDM4EALDH1A1POLBLMNA | |
| SCHEMBL20077346 | 0.68 | MAPT (0.38) | KDM4EALDH1A1HSD17B10HTTPOLB | |
| SCHEMBL10277395 | 0.67 | MAPT (0.40) | KDM4EALDH1A1HSD17B10HTTPOLB | |
| SCHEMBL15979212 | 0.67 | RAB9A (0.38) | KDM4EALDH1A1HPGDPOLBSMN1; SMN2 | |
| SCHEMBL26194060 | 0.66 | MAPT (0.48) | KDM4EALDH1A1LMNASMN1; SMN2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071348-A1 | QUINOXALINE COMPOUNDS AS TYPE III RECEPTOR TYROSINE KINASE INHIBITORS | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 2018-04-19 | — | — | WO | disclosed |