Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 3/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22894978 | 1.00 | NR1H2 (0.41) | NR1H2NR1H3ROCK2PRKG1CHRM4 | |
| SCHEMBL20077550 | 0.86 | NR1H2 (0.53) | NR1H2NR1H3ROCK2PRKG1CHRM4 | |
| SCHEMBL20077155 | 0.86 | NR1H2 (0.53) | NR1H2NR1H3ROCK2PRKG1CHRM4 | |
| SCHEMBL22895048 | 0.86 | NR1H2 (0.53) | NR1H2NR1H3ROCK2PRKG1CHRM4 | |
| SCHEMBL20077156 | 0.86 | NR1H2 (0.53) | NR1H2NR1H3ROCK2PRKG1CHRM4 | |
| SCHEMBL20077551 | 0.86 | NR1H2 (0.53) | NR1H2NR1H3ROCK2PRKG1CHRM4 | |
| SCHEMBL20060866 | 0.85 | GPR119 (0.44) | NR1H2NR1H3PDK2FFAR1GPR119 | |
| SCHEMBL20077739 | 0.85 | NR1H2 (0.38) | NR1H2NR1H3PDK2FFAR1GPR119 | |
| SCHEMBL20077652 | 0.83 | NR1H2 (0.39) | NR1H2NR1H3KMT2APDK2FFAR1 | |
| SCHEMBL22363661 | 0.81 | NR1H2 (0.49) | NR1H2NR1H3ROCK2CHRM4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071315-A2 | PIPERIDINE DERIVATIVES AS LIVER X RECEPTOR BETA AGONISTS, COMPOSITIONS, AND THEIR USE | MERCK SHARP & DOHME CORP. (US) | 2018-04-19 | — | — | WO | disclosed |