Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20128071 | 0.82 | CYP2C19 (0.38) | POLBLMNATSHR | |
| SCHEMBL23253661 | 0.81 | POLB (0.34) | POLBLMNA | |
| SCHEMBL21432044 | 0.79 | POLB (0.33) | POLB | |
| SCHEMBL20077525 | 0.75 | LMNA (0.32) | POLBLMNA | |
| SCHEMBL21161442 | 0.73 | POLB (0.33) | POLBLMNAGAA | |
| SCHEMBL9547482 | 0.73 | — | — | |
| SCHEMBL20476067 | 0.72 | POLB (0.32) | POLBLMNA | |
| SCHEMBL13545394 | 0.72 | CYP2C19 (0.47) | LMNATSHR | |
| Hydrochloric Acid SCHEMBL21080159 | 0.71 | POLB (0.31) | POLBLMNA | |
| SCHEMBL17446962 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071620-A1 | HETEROCYCLIC SULFONES AS ROR GAMMA MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-04-19 | — | — | WO | disclosed |