SCHEMBL20078088

SCHEMBL20078088

CCCCCCCC/C=C\CC(=O)OC[C@@H](O)COP(=O)(O)O

nearest known ligand 0.81

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LPAR1 Q92633 9/20 0.81
ENPP2 Q13822 4/20 0.81
LPAR4 Q99677 4/20 0.81
LPAR2 Q9HBW0 4/20 0.81
LPAR3 Q9UBY5 4/20 0.81
LPAR5 Q9H1C0 3/20 0.81
LPAR6 P43657 2/20 0.81
CES2 O00748 1/20 0.81
TRPV1 Q8NER1 1/20 0.81
P2RY10 O00398 6/20 0.59
GPR174 Q9BXC1 6/20 0.59
GPR34 Q9UPC5 3/20 0.59
DGKA P23743 1/20 0.55
GPR55 Q9Y2T6 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lysophosphatidic Acid SCHEMBL1548 0.90 LPAR1 (1.00) LPAR1ENPP2LPAR4LPAR2LPAR3
SCHEMBL6360211 0.90 LPAR1 (1.00) LPAR1ENPP2LPAR4LPAR2LPAR3
SCHEMBL6356574 0.90 LPAR1 (1.00) LPAR1ENPP2LPAR4LPAR2LPAR3
Lysophosphatidic Acid SCHEMBL3672549 0.90 LPAR1 (1.00) LPAR1ENPP2LPAR4LPAR2LPAR3
Lysophosphatidic Acid SCHEMBL12388925 0.90 LPAR1 (1.00) LPAR1ENPP2LPAR4LPAR2LPAR3
SCHEMBL6349896 0.90 LPAR1 (1.00) LPAR1ENPP2LPAR4LPAR2LPAR3
SCHEMBL6349984 0.90 LPAR1 (1.00) LPAR1ENPP2LPAR4LPAR2LPAR3
SCHEMBL6340952 0.90 LPAR1 (1.00) LPAR1ENPP2LPAR4LPAR2LPAR3
SCHEMBL6360208 0.90 LPAR1 (1.00) LPAR1ENPP2LPAR4LPAR2LPAR3
SCHEMBL6336799 0.90 LPAR1 (1.00) LPAR1ENPP2LPAR4LPAR2LPAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9952231-B2 Lysophosphatidic acid detection PORTLAND STATE UNIVERSITY (US) 2018-04-24 US disclosed