Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | CASP1 | P29466 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MERTK | Q12866 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20078409 | 0.87 | POLR1A (0.37) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL18057405 | 0.86 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL17255051 | 0.84 | MKNK1 (0.52) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL23161881 | 0.84 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL18057394 | 0.83 | KDM4E (0.48) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL18057384 | 0.82 | ALDH1A1 (0.57) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL20078424 | 0.82 | MKNK1 (0.43) | KDM4EALDH1A1GAACASP1HSD17B10 | |
| SCHEMBL20078411 | 0.81 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL20078422 | 0.78 | KDM4E (0.39) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL20078412 | 0.76 | BRD4 (0.43) | MAPK8LCKKDRMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951066-B2 | Compositions, uses and methods for making them | Pimera, Inc. (US) | 2018-04-24 | — | — | US | disclosed |