Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 20/20 | 0.48 |
| ▸ | HTR1A | P08908 | 16/20 | 0.48 |
| ▸ | HTR2A | P28223 | 16/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL251847 | 0.81 | DRD2 (0.56) | DRD2HTR1AHTR2A | |
| SCHEMBL5221533 | 0.79 | DRD2 (0.53) | DRD2HTR1AHTR2A | |
| SCHEMBL5249304 | 0.78 | DRD2 (0.41) | DRD2HTR1AHTR2A | |
| SCHEMBL5369042 | 0.76 | DRD2 (0.39) | DRD2HTR1AHTR2A | |
| SCHEMBL5374824 | 0.75 | DRD2 (0.40) | DRD2HTR1AHTR2A | |
| SCHEMBL14984327 | 0.71 | DRD2 (0.58) | DRD2HTR1AHTR2A | |
| SCHEMBL5374311 | 0.71 | DRD2 (0.39) | DRD2HTR1AHTR2A | |
| SCHEMBL6102729 | 0.71 | DRD2 (0.39) | DRD2HTR1AHTR2A | |
| SCHEMBL16559722 | 0.71 | DRD2 (0.70) | DRD2HTR1AHTR2A | |
| SCHEMBL16559741 | 0.70 | DRD2 (0.67) | DRD2HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951088-B2 | D2 receptor modulators and methods of use thereof in the treatment of diseases and disorders | SUNOVION PHARMACEUTICALS INC. (US) | 2018-04-24 | — | — | US | disclosed |