Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 14/20 | 0.66 |
| ▸ | CA2 | P00918 | 14/20 | 0.66 |
| ▸ | CA9 | Q16790 | 14/20 | 0.66 |
| ▸ | CA12 | O43570 | 7/20 | 0.66 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.66 |
| ▸ | CA7 | P43166 | 1/20 | 0.66 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.63 |
| ▸ | HTR3A | P46098 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14411392 | 0.89 | CA1 (0.66) | CA1CA2CA9CA12CA14 | |
| SCHEMBL14089616 | 0.88 | CA9 (0.73) | CA1CA2CA9CA12CA14 | |
| SCHEMBL17793595 | 0.87 | CA9 (0.72) | CA1CA2CA9CA12CA14 | |
| SCHEMBL14032096 | 0.87 | CA9 (0.72) | CA1CA2CA9CA12CA14 | |
| SCHEMBL17049667 | 0.87 | CA9 (0.74) | CA1CA2CA9CA12CA14 | |
| SCHEMBL21391543 | 0.87 | CA9 (0.69) | CA1CA2CA9CA12CA14 | |
| SCHEMBL20622624 | 0.86 | CA9 (0.75) | CA1CA2CA9CA12CA14 | |
| SCHEMBL12185092 | 0.86 | CA9 (0.73) | CA1CA2CA9CA12CA14 | |
| SCHEMBL24257626 | 0.86 | CA9 (0.70) | CA1CA2CA9CA12CA14 | |
| SCHEMBL21303554 | 0.86 | CA9 (0.72) | CA1CA2CA9CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951324-B2 | PSMA binding ligand-linker conjugates and methods for using | PURDUE RESEARCH FOUNDATION (US) | 2018-04-24 | — | — | US | disclosed |