SCHEMBL21391543

SCHEMBL21391543

CC(C)NCCNC(=S)Nc1ccc(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c(C(=O)O)c1

nearest known ligand 0.69

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ CA9 Q16790 15/20 0.69
▸ CA1 P00915 14/20 0.69
▸ CA2 P00918 14/20 0.69
▸ CA12 O43570 6/20 0.69
▸ CA14 Q9ULX7 2/20 0.69
▸ CA7 P43166 2/20 0.69
▸ ELF3 P78545 1/20 0.58
▸ MED23 Q9ULK4 1/20 0.58
▸ FKBP1A P62942 2/20 0.58
▸ HTR3A P46098 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12185010 0.91 CA9 (0.70) CA9CA1CA2CA12CA14
SCHEMBL14032096 0.91 CA9 (0.72) CA9CA1CA2CA12CA14
SCHEMBL17793595 0.91 CA9 (0.72) CA9CA1CA2CA12CA14
SCHEMBL14089616 0.90 CA9 (0.73) CA9CA1CA2CA12CA14
SCHEMBL12185092 0.90 CA9 (0.73) CA9CA1CA2CA12CA14
SCHEMBL24257626 0.89 CA9 (0.70) CA9CA1CA2CA12CA14
SCHEMBL15958213 0.89 CA9 (0.70) CA9CA1CA2CA12CA14
SCHEMBL17049667 0.89 CA9 (0.74) CA9CA1CA2CA12CA14
SCHEMBL21186772 0.89 CA9 (0.65) CA9CA1CA2CA12CA14
SCHEMBL15910186 0.89 CA1 (0.68) CA9CA1CA2CA12CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220047725-A1 CHEMILUMINESCENT PROBES FOR DIAGNOSTICS AND IN VIVO IMAGING RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2022-02-17 — — US disclosed
US-11179482-B2 Chemiluminescent probes for diagnostics and in vivo imaging RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2021-11-23 — — US disclosed
US-20200237932-A1 CHEMILUMINESCENT PROBES FOR DIAGNOSTICS AND IN VIVO IMAGING RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2020-07-30 — — US disclosed
US-10660974-B2 Chemiluminescent probes for diagnostics and in vivo imaging RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2020-05-26 — — US disclosed
US-20190290787-A1 CHEMILUMINESCENT PROBES FOR DIAGNOSTICS AND IN VIVO IMAGING RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2019-09-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10660974-B2 Chemiluminescent probes for diagnostics and in vivo imaging DAXX, DCAF15, DCAF1 CA9 568/4885CA1 1716/4885CA2 2871/4885
US-20200237932-A1 CHEMILUMINESCENT PROBES FOR DIAGNOSTICS AND IN VIVO IMAGING DAXX, DCAF15, CDY1; CDY1B CA9 370/4885CA1 504/4885CA2 1996/4885
US-20220047725-A1 CHEMILUMINESCENT PROBES FOR DIAGNOSTICS AND IN VIVO IMAGING DAXX, DCAF15, CDY1; CDY1B CA9 370/4885CA1 504/4885CA2 1996/4885
US-11179482-B2 Chemiluminescent probes for diagnostics and in vivo imaging DAXX, DCAF15, CDY1; CDY1B CA9 370/4885CA1 504/4885CA2 1996/4885
US-20190290787-A1 CHEMILUMINESCENT PROBES FOR DIAGNOSTICS AND IN VIVO IMAGING DAXX, DCAF15, DCAF1 CA9 568/4885CA1 1716/4885CA2 2871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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