Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19241405 | 1.00 | MAPK1 (0.37) | MAPK1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL5077931 | 0.73 | MAPK1 (0.39) | MAPK1MEN1KMT2A | |
| SCHEMBL5077933 | 0.73 | MAPK1 (0.39) | MAPK1MEN1KMT2A | |
| SCHEMBL5077934 | 0.73 | MAPK1 (0.39) | MAPK1MEN1KMT2A | |
| SCHEMBL1089769 | 0.73 | — | — | |
| SCHEMBL918389 | 0.69 | MAPK1 (0.41) | MAPK1MEN1KMT2A | |
| SCHEMBL8348683 | 0.67 | — | — | |
| SCHEMBL13286401 | 0.66 | HSD11B1 (0.30) | — | |
| SCHEMBL8344708 | 0.65 | SMN1; SMN2 (0.38) | MAPK1MEN1KMT2A | |
| SCHEMBL12844775 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9950983-B2 | Tricyclic compounds and process for preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2018-04-24 | — | — | US | disclosed |