Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 13/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | BPTF | Q12830 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18233551 | 0.86 | KAT2B (0.43) | KAT2BGAAL3MBTL1BPTFKDM4E | |
| SCHEMBL19720601 | 0.81 | KAT2B (0.40) | KAT2BGAAL3MBTL1BPTFKDM4E | |
| SCHEMBL13766252 | 0.80 | KAT2B (0.39) | KAT2BGAAL3MBTL1BPTFKDM4E | |
| SCHEMBL23977662 | 0.80 | KAT2B (0.39) | KAT2BGAAL3MBTL1BPTFKDM4E | |
| SCHEMBL22303403 | 0.80 | KAT2B (0.39) | KAT2BGAAL3MBTL1BPTFKDM4E | |
| SCHEMBL20922476 | 0.77 | GAA (0.43) | GAAL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL20621874 | 0.74 | KAT2B (0.34) | KAT2BGAAL3MBTL1BPTFKDM4E | |
| SCHEMBL18236735 | 0.74 | KAT2B (0.34) | KAT2BGAAL3MBTL1BPTFKDM4E | |
| SCHEMBL14472668 | 0.74 | KAT2B (0.34) | KAT2BGAAL3MBTL1BPTFKDM4E | |
| SCHEMBL15281313 | 0.74 | KAT2B (0.41) | KAT2BBPTF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951065-B2 | Benzimidazole and imadazopyridine carboximidamide compounds | GILEAD SCIENCES, INC. (US) | 2018-04-24 | — | — | US | disclosed |