SCHEMBL22303403

SCHEMBL22303403

CC(C)N[C@H]1CCCN(C)C1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KAT2B Q92831 12/20 0.39
BPTF Q12830 1/20 0.39
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 1/20 0.36
GAA P10253 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ROCK2 O75116 1/20 0.33
ROCK1 Q13464 1/20 0.33
CDC42BPB Q9Y5S2 1/20 0.33
EHMT2 Q96KQ7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23977662 1.00 KAT2B (0.39) KAT2BBPTFKDM4EALDH1A1GAA
SCHEMBL13766252 1.00 KAT2B (0.39) KAT2BBPTFKDM4EALDH1A1GAA
SCHEMBL18233551 0.94 KAT2B (0.43) KAT2BBPTFKDM4EALDH1A1GAA
SCHEMBL14472668 0.89 KAT2B (0.34) KAT2BBPTFKDM4EALDH1A1GAA
SCHEMBL20621874 0.89 KAT2B (0.34) KAT2BBPTFKDM4EALDH1A1GAA
SCHEMBL18236735 0.89 KAT2B (0.34) KAT2BBPTFKDM4EALDH1A1GAA
SCHEMBL22055532 0.83 GAA (0.42) KAT2BBPTFKDM4EALDH1A1GAA
SCHEMBL18183344 0.83 KDM4E (0.40) KAT2BKDM4EALDH1A1GAAL3MBTL1
SCHEMBL19720601 0.80 KAT2B (0.40) KAT2BBPTFKDM4EALDH1A1GAA
SCHEMBL20079253 0.80 KAT2B (0.40) KAT2BBPTFKDM4EALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230053746-A1 IL-17 LIGANDS AND USES THEREOF DICE MOLECULES SV, INC. 2023-02-23 US disclosed
US-20200247785-A1 IL-17 Ligands And Uses Thereof DICE MOLECULES SV, INC. 2020-08-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230053746-A1 IL-17 LIGANDS AND USES THEREOF IL17A, IL2, IL15 KAT2B 4205/4885BPTF 2365/4885KDM4E 4390/4885
US-20200247785-A1 IL-17 Ligands And Uses Thereof IL17A, IL2, IL15 KAT2B 4205/4885BPTF 2365/4885KDM4E 4390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.