Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4451075 | 0.83 | AR (0.46) | ARESR1ESR2CYP17A1CYP11B1 | |
| SCHEMBL5949232 | 0.73 | AR (0.40) | ARESR1ESR2CYP17A1CYP11B1 | |
| SCHEMBL29006506 | 0.73 | AMY1A (0.41) | ARESR1ESR2 | |
| SCHEMBL19996627 | 0.72 | PIM1 (0.41) | — | |
| SCHEMBL1512796 | 0.72 | PIM1 (0.41) | ARESR1ESR2 | |
| SCHEMBL29987655 | 0.72 | PIM1 (0.41) | ARESR1ESR2 | |
| SCHEMBL12196477 | 0.71 | AR (0.42) | ARESR1ESR2CYP17A1CYP11B1 | |
| SCHEMBL20079322 | 0.71 | KDM4E (0.36) | ESR1ESR2 | |
| SCHEMBL4744474 | 0.70 | AR (0.41) | ARESR1ESR2CYP17A1CYP11B1 | |
| SCHEMBL25420346 | 0.70 | NPC1 (0.46) | ARESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951274-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2018-04-24 | — | — | US | disclosed |