Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14654994 | 0.89 | ALDH1A1 (0.36) | FOLH1ALDH1A1GAAMAPTNPC1 | |
| SCHEMBL24368314 | 0.83 | ALDH1A1 (0.37) | ALDH1A1GAAMAPTNPC1RAB9A | |
| SCHEMBL18119783 | 0.82 | FOLH1 (0.51) | FOLH1ALDH1A1GAASMN1; SMN2TSHR | |
| SCHEMBL23695819 | 0.81 | ALDH1A1 (0.34) | ALDH1A1GAAMAPTNPC1RAB9A | |
| SCHEMBL15910121 | 0.81 | ALDH1A1 (0.46) | ALDH1A1GAAMAPTNPC1RAB9A | |
| SCHEMBL17324231 | 0.81 | ALDH1A1 (0.42) | FOLH1ALDH1A1GAAMAPTNPC1 | |
| SCHEMBL18822933 | 0.80 | ALDH1A1 (0.43) | FOLH1ALDH1A1GAANPC1RAB9A | |
| SCHEMBL10075279 | 0.79 | MAPT (0.39) | ALDH1A1GAAMAPTNPC1RAB9A | |
| SCHEMBL16327597 | 0.79 | TSHR (0.48) | FOLH1ALDH1A1GAARAB9ATSHR | |
| SCHEMBL14296139 | 0.78 | FOLH1 (0.34) | FOLH1ALDH1A1GAATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022082312-A1 | NOVEL CXCR4-TARGETING COMPOUNDS | PROVINCIAL HEALTH SERVICES AUTHORITY (CA) | 2022-04-28 | — | — | WO | disclosed |
| US-9950075-B2 | Compositions and methods for delivering agents to the central nervous system | THE UNIVERSITY OF MASSACHUSETTS (US) | 2018-04-24 | — | — | US | disclosed |