Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 15/20 | 0.65 |
| ▸ | WNT3A | P56704 | 10/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19560289 | 0.87 | CTNNB1 (0.57) | CTNNB1WNT3ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL652411 | 0.82 | CTNNB1 (0.84) | CTNNB1WNT3AHPGDPKMTSHR | |
| SCHEMBL654664 | 0.79 | CTNNB1 (1.00) | CTNNB1WNT3AALDH1A1LMNAMAPT | |
| SCHEMBL20079916 | 0.78 | CTNNB1 (0.77) | CTNNB1WNT3ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL30440765 | 0.77 | CTNNB1 (1.00) | CTNNB1WNT3AHPGDPKMTSHR | |
| SCHEMBL15969450 | 0.77 | CTNNB1 (1.00) | CTNNB1WNT3AHPGDPKMTSHR | |
| SCHEMBL653474 | 0.76 | CTNNB1 (0.74) | CTNNB1WNT3AHPGDPKMTSHR | |
| SCHEMBL653025 | 0.75 | PKM (0.87) | CTNNB1WNT3AALDH1A1HPGDPKM | |
| SCHEMBL15968604 | 0.75 | CTNNB1 (1.00) | CTNNB1WNT3AHPGDPKMTSHR | |
| SCHEMBL20079919 | 0.75 | CTNNB1 (0.91) | CTNNB1WNT3ASMN1; SMN2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3311666-A1 | DIKETONES AND HYDROXYKETONES AS CATENIN SIGNALING PATHWAY ACTIVATORS | Samumed, LLC (US) | 2018-04-25 | — | — | EP | disclosed |