Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | CTNNB1 | P35222 | 15/20 | 0.70 |
| ▸ | WNT3A | P56704 | 10/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20079901 | 0.91 | CTNNB1 (0.81) | PKMTSHRCTNNB1WNT3AHPGD | |
| SCHEMBL20079913 | 0.91 | CTNNB1 (0.81) | PKMTSHRCTNNB1WNT3AALDH1A1 | |
| SCHEMBL19560214 | 0.91 | CTNNB1 (0.67) | PKMTSHRCTNNB1WNT3AHPGD | |
| SCHEMBL653025 | 0.90 | PKM (0.87) | PKMTSHRCTNNB1WNT3AHPGD | |
| SCHEMBL1443787 | 0.84 | PKM (1.00) | PKMTSHRCTNNB1WNT3AHPGD | |
| SCHEMBL20079912 | 0.83 | CTNNB1 (0.81) | PKMTSHRCTNNB1WNT3AHPGD | |
| Dalosirvat SCHEMBL653870 | 0.83 | CTNNB1 (1.00) | PKMTSHRCTNNB1WNT3AHPGD | |
| SCHEMBL652627 | 0.83 | CTNNB1 (0.77) | PKMTSHRCTNNB1WNT3AHPGD | |
| SCHEMBL10027736 | 0.81 | CTNNB1 (1.00) | PKMTSHRCTNNB1WNT3AHPGD | |
| SCHEMBL654022 | 0.81 | CTNNB1 (1.00) | PKMTSHRCTNNB1WNT3AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3311666-A1 | DIKETONES AND HYDROXYKETONES AS CATENIN SIGNALING PATHWAY ACTIVATORS | Samumed, LLC (US) | 2018-04-25 | — | — | EP | disclosed |