Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 11/20 | 0.79 |
| ▸ | WNT3A | P56704 | 9/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL652034 | 0.88 | CTNNB1 (1.00) | CTNNB1WNT3ANPC1RAB9AKMT2A | |
| SCHEMBL7431727 | 0.79 | CTNNB1 (0.71) | CTNNB1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL2470002 | 0.78 | CTNNB1 (0.71) | CTNNB1WNT3AKMT2AALDH1A1LMNA | |
| SCHEMBL15980176 | 0.72 | CTNNB1 (0.65) | CTNNB1WNT3AKMT2AALDH1A1LMNA | |
| SCHEMBL4743860 | 0.72 | CTNNB1 (0.63) | CTNNB1WNT3AKMT2AALDH1A1LMNA | |
| SCHEMBL30609612 | 0.72 | CTNNB1 (0.63) | CTNNB1WNT3AKMT2AALDH1A1LMNA | |
| SCHEMBL15980186 | 0.71 | CTNNB1 (0.69) | CTNNB1WNT3ANPC1RAB9AKMT2A | |
| SCHEMBL15980187 | 0.71 | LMNA (0.72) | CTNNB1WNT3ANPC1RAB9AKMT2A | |
| SCHEMBL15980180 | 0.71 | CTNNB1 (0.60) | CTNNB1WNT3ANPC1RAB9AKMT2A | |
| SCHEMBL12857648 | 0.71 | CTNNB1 (0.60) | CTNNB1NPC1RAB9AKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3311666-A1 | DIKETONES AND HYDROXYKETONES AS CATENIN SIGNALING PATHWAY ACTIVATORS | Samumed, LLC (US) | 2018-04-25 | — | — | EP | disclosed |