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Sugi Predict / Compounds / SCHEMBL20079966

SCHEMBL20079966

SCHEMBL20079966

C1=Cc2c(oc3c(-c4ccc(-c5ccc(N(c6ccc(-c7cccc8c7oc7ccccc78)cc6)c6ccc7c8ccccc8c8ccccc8c7c6)cc5)cc4)cccc23)CCC1

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 2/20 0.39
▸ PRKDC P78527 2/20 0.35
▸ PRMT5 O14744 1/20 0.32
▸ WDR77 Q9BQA1 1/20 0.32
▸ PTGES2 Q9H7Z7 1/20 0.32
▸ GGPS1 O95749 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24627623 0.86 ALOX5 (0.41) ALOX5PRKDCPRMT5WDR77PTGES2
SCHEMBL23584424 0.86 ALOX5 (0.41) ALOX5PRKDCPRMT5WDR77PTGES2
SCHEMBL16067898 0.86 ALOX5 (0.41) ALOX5PRKDCPRMT5WDR77PTGES2
SCHEMBL24118933 0.86 ALOX5 (0.41) ALOX5PRKDCPRMT5WDR77PTGES2
SCHEMBL25452875 0.86 ALOX5 (0.40) ALOX5PRKDCPRMT5WDR77PTGES2
SCHEMBL16883191 0.84 ALOX5 (0.53) ALOX5PRKDCPRMT5WDR77PTGES2
SCHEMBL16883142 0.84 ALOX5 (0.53) ALOX5PRKDCPRMT5WDR77PTGES2
SCHEMBL12283700 0.83 ALOX5 (0.38) ALOX5PRKDCPRMT5WDR77PTGES2
SCHEMBL16883071 0.82 ALOX5 (0.55) ALOX5PRKDCPRMT5WDR77PTGES2
SCHEMBL16883028 0.82 ALOX5 (0.55) ALOX5PRKDCPRMT5WDR77PTGES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3312167-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME Idemitsu Kosan Co., Ltd. (JP) 2018-04-25 — — EP disclosed
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