Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | AGXT | P21549 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10819594 | 0.83 | IDO1 (0.52) | IDO1AGXTPPARGPPARACA1 | |
| SCHEMBL12722434 | 0.81 | ADRB2 (0.38) | IDO1PPARGPPARACA1CA2 | |
| SCHEMBL28452339 | 0.79 | IDO1 (0.48) | IDO1AGXTPPARGPPARACA1 | |
| SCHEMBL18133061 | 0.78 | RCE1 (0.49) | IDO1CA1CA2CA9HTT | |
| SCHEMBL51132 | 0.78 | RCE1 (0.49) | IDO1CA1CA2CA9HTT | |
| SCHEMBL13209409 | 0.78 | IDO1 (0.47) | IDO1AGXTPPARGPPARACA1 | |
| SCHEMBL13262551 | 0.78 | POLB (0.42) | IDO1AGXTPPARACA1CA2 | |
| SCHEMBL20045400 | 0.77 | PPARG (0.57) | PPARGPPARACA1CA2MMP2 | |
| SCHEMBL28072230 | 0.77 | PPARG (0.47) | IDO1AGXTPPARGPPARACA1 | |
| SCHEMBL6964566 | 0.77 | RCE1 (0.47) | IDO1CA1CA2CA9HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2751076-B1 | SYNTHESIS METHOD AND INTERMEDIATES USEFUL IN THE PREPARATION OF PYRROLOBENZODIAZEPINES | MEDIMMUNE LTD (GB) | 2018-04-25 | — | — | EP | disclosed |