Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | HTR3A | P46098 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20080410 | 0.91 | HTR3A (0.51) | KMT2AHTR3AL3MBTL1TSHRHTR7 | |
| SCHEMBL15444633 | 0.86 | HTR3A (0.56) | KMT2AHTR3AHTR7POLBALDH1A1 | |
| SCHEMBL19969879 | 0.86 | HTR3A (0.54) | KMT2AHTR3AL3MBTL1TSHRMEN1 | |
| SCHEMBL6044056 | 0.83 | HTR3A (0.53) | HTR3AL3MBTL1TSHRHTR7POLB | |
| SCHEMBL15440779 | 0.81 | HTR3A (0.54) | HTR3ATSHRHTR7POLBALDH1A1 | |
| SCHEMBL15420930 | 0.81 | NR4A2 (0.64) | KMT2AHTR3AL3MBTL1TSHRMEN1 | |
| SCHEMBL20080370 | 0.81 | HTR3A (0.54) | KMT2AHTR3AL3MBTL1TSHRMEN1 | |
| SCHEMBL18539469 | 0.80 | HTR3A (0.46) | KMT2AHTR3ATSHRMEN1HTR7 | |
| SCHEMBL23812575 | 0.80 | KMT2A (0.53) | KMT2AHTR3AL3MBTL1TSHRMEN1 | |
| SCHEMBL19068175 | 0.79 | HTR3A (0.53) | KMT2AHTR3AL3MBTL1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312169-B1 | 5-HT3 RECEPTOR ANTAGONISTS | TAKEDA PHARMACEUTICALS CO (JP) | 2021-09-15 | — | — | EP | disclosed |
| EP-3312169-A1 | 5-HT3 RECEPTOR ANTAGONISTS | Takeda Pharmaceutical Company Limited (JP) | 2018-04-25 | — | — | EP | disclosed |