Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 12/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17652247 | 0.87 | HTR3A (0.59) | HTR3ANR4A2ENPP2 | |
| SCHEMBL18922760 | 0.85 | HTR3A (0.58) | HTR3AKMT2AL3MBTL1TSHRNR4A2 | |
| SCHEMBL15444637 | 0.85 | HTR3A (0.58) | HTR3AL3MBTL1NR4A2ENPP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL15421042 | 0.85 | HTR3A (0.58) | HTR3ANR4A2ENPP2 | |
| SCHEMBL15440798 | 0.82 | HTR3A (0.58) | HTR3ATSHRNR4A2ALDH1A1 | |
| SCHEMBL15420954 | 0.82 | NR4A2 (0.69) | HTR3AKMT2AL3MBTL1TSHRNR4A2 | |
| SCHEMBL23812548 | 0.81 | HTR3A (0.53) | HTR3AKMT2AL3MBTL1TSHRNR4A2 | |
| SCHEMBL23812575 | 0.80 | KMT2A (0.53) | HTR3AKMT2AL3MBTL1TSHRNR4A2 | |
| SCHEMBL19068198 | 0.80 | HTR3A (0.53) | HTR3AKMT2AL3MBTL1TSHRNR4A2 | |
| SCHEMBL18922736 | 0.79 | HTR3A (0.54) | HTR3AKMT2AL3MBTL1TSHRNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312169-A1 | 5-HT3 RECEPTOR ANTAGONISTS | Takeda Pharmaceutical Company Limited (JP) | 2018-04-25 | — | — | EP | disclosed |