Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15694788 | 0.84 | HTT (0.55) | LMNAMAPTALDH1A1KDM4ENFKB1 | |
| SCHEMBL15694789 | 0.76 | NPC1 (0.67) | MAPTALDH1A1KDM4ENPSR1MEN1 | |
| SCHEMBL17503146 | 0.72 | HPGD (0.43) | LMNAMAPTALDH1A1KDM4ENPSR1 | |
| SCHEMBL17503145 | 0.72 | HPGD (0.43) | LMNAMAPTALDH1A1KDM4ENPSR1 | |
| SCHEMBL17539208 | 0.72 | HPGD (0.43) | LMNAMAPTALDH1A1KDM4ENPSR1 | |
| SCHEMBL17211855 | 0.72 | POLB (0.57) | LMNAMAPTALDH1A1KDM4ENFKB1 | |
| SCHEMBL18460775 | 0.72 | NPSR1 (0.59) | LMNAMAPTALDH1A1KDM4ENFKB1 | |
| SCHEMBL15672269 | 0.70 | KDM4E (0.77) | LMNAMAPTALDH1A1KDM4ENPSR1 | |
| SCHEMBL17211853 | 0.70 | NPC1 (0.66) | LMNAMAPTALDH1A1KDM4ENPSR1 | |
| SCHEMBL29773615 | 0.70 | NCOA3 (0.49) | LMNAMAPTALDH1A1KDM4ENFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2915806-B1 | QUINOLINE COMPOUND AND USE THEREOF | UNIV SHENYANG PHARMACEUTICAL (CN) | 2018-04-25 | — | — | EP | disclosed |